Metal-free three-component assemblies of anilines, α-keto acids and alkyl lactates for quinoline synthesis and their anti-inflammatory activity-Reference-Cited by-同舟云学术

Metal-free three-component assemblies of anilines, α-keto acids and alkyl lactates for quinoline synthesis and their anti-inflammatory activity

Published:2022 Issue:21 Volume:20 Page:4385-4390
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Huang Lizhu¹,Yang Lu¹,Wan Jie-Ping¹^ORCID,Zhou Liyun¹,Liu Yunyun¹^ORCID,Hao Guifeng²

Affiliation:

1. College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, China

2. Center for General Practice Medicine, Department of Rheumatology and Immunology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou 310014, Zhejiang, China

Abstract

A metal-free three-component protocol for quinoline synthesis is developed by using alkyl lactates, anilines and α-keto acids. In vitro experiments disclose the attractive anti-inflammatory activity of these quinoline compounds.

Funder

Natural Science Foundation of Jiangxi Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00661H

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