Enhanced vascularization of PCL porous scaffolds through VEGF-Fc modification-Reference-Cited by-同舟云学术

Enhanced vascularization of PCL porous scaffolds through VEGF-Fc modification

Published:2018 Issue:27 Volume:6 Page:4474-4485
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Xu Ke¹²³⁴⁵,Zhu Chuanshun⁶⁷⁵⁸,Xie Jinghui¹²³⁴⁵,Li Xiaoning¹²³⁴⁵,Zhang Yan¹²³⁴⁵,Yao Fanglian⁶⁷⁵⁸^ORCID,Gu Zhongwei⁹¹⁰¹¹¹²¹³,Yang Jun¹²³⁴⁵^ORCID

Affiliation:

1. The Key Laboratory of Bioactive Materials

2. Ministry of Education

3. College of Life Science

4. Nankai University

5. Tianjin

6. School of Chemical Engineering

7. Tianjin University

8. China

9. College of Materials Science & Engineering

10. Research Institute of New Materials

11. Institute of Biomaterials

12. Nanjing Tech University

13. Nanjing

Abstract

VEGF-Fc interface improves the vascularization of PCL scaffolds by enhancing HUVEC proliferation and migration through activating VEGFR/Pi3k and VEGFR/MAPK pathways.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Tianjin City

Beijing Municipal Commission of Education

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2018/TB/C8TB00624E

Reference50 articles.

1. Polymer-based mesh as supports for multi-layered 3D cell culture and assays

2. Vascularization is the key challenge in tissue engineering

3. Vascularization in tissue engineering

4. Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling

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