An improved soluble polynorbornene support for peptide synthesis
Author:
Affiliation:
1. Department of Chemistry
2. Indian Institute of Technology
3. Chennai
4. India
Abstract
A soluble polynorbornene support containing an oligoether linker as well as alkyl and oligoether side chains has been developed and used to synthesize Leu5-Enkephalin in 52% overall yield using only 1.2 equivalents of coupling reagents.
Funder
Council for Scientific and Industrial Research
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA21668K
Reference29 articles.
1. Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide
2. Peptide synthesis by the soluble-polymer technique
3. Liquid Phase Peptide Synthesis by the Fragment Condensation on Soluble Polymer Support. II. The Azide Method
4. Synthesis of peptides in solution on a polymeric support I. Synthesis of glycylglycyl-l-leucylglycine
5. Liquid Phase Synthesis of Peptides
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