Combinatorial chemistry in nematodes: modular assembly of primary metabolism-derived building blocks
Author:
Affiliation:
1. Max Planck Institute for Chemical Ecology
2. Department of Bioorganic Chemistry
3. Jena
4. Germany
5. Boyce Thompson Institute and Department of Chemistry and Chemical Biology
6. Cornell University
7. Ithaca
8. USA
Abstract
Nematodes are amazingly skilled chemists: using simple building blocks from conserved primary metabolism and a strategy of modular assembly, C. elegans and other nematode species create complex molecular architectures to regulate their development and behaviour.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/NP/C5NP00042D
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