Dinuclear nickel(<scp>ii</scp>) supramolecular helicates down-regulate gene expression in human cells by stabilizing DNA G-quadruplexes formed in the promoter regions-Reference-Cited by-同舟云学术

Dinuclear nickel(ii) supramolecular helicates down-regulate gene expression in human cells by stabilizing DNA G-quadruplexes formed in the promoter regions

Published:2022 Issue:21 Volume:9 Page:5597-5606
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Malina Jaroslav¹^ORCID,Kostrhunova Hana¹^ORCID,Brabec Viktor¹^ORCID

Affiliation:

1. Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic

Abstract

Dinuclear nickel(ii) supramolecular helicates selectively stabilize DNA G-quadruplexes and suppress G-quadruplex-regulated genes.

Funder

Grantová Agentura České Republiky

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QI/D2QI01435A

Reference49 articles.

1. An inexpensive approach to supramolecular architecture

2. Intramolecular DNA coiling mediated by metallo-supramolecular cylinders: Differential binding of P and M helical enantiomers

3. Intramolecular DNA Coiling Mediated by a Metallo-Supramolecular Cylinder

4. DNA binding of dinuclear iron(II) metallosupramolecular cylinders. DNA unwinding and sequence preference

5. Molecular Recognition of a Three-Way DNA Junction by a Metallosupramolecular Helicate

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