Structural characterization, anti-inflammatory and glycosidase inhibitory activities of two new polysaccharides from the root of Pueraria lobata

Author:

Cai Jiale123ORCID,Zhong Xiaoting123,Liang Jiayin123,Xu Can123,Yu Huanzheng123,Xian Minghua123ORCID,Yan Chunyan1,Wang Shumei123ORCID

Affiliation:

1. Guangdong Pharmaceutical University, Guangzhou 510006, China

2. Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China

3. Engineering & Technology Research Center for Chinese Materia Medica Quality of the Universities of Guangdong Province, School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China

Abstract

Through the extraction, isolation and purification of Pueraria lobata, we identified two new polysaccharides with molecular weights of 9.1 × 103 Da and 3.8 × 103 Da, and found that they have excellent anti-inflammatory and glycosidase inhibitory effects.

Funder

National Natural Science Foundation of China

State Administration of Traditional Chinese Medicine of the People's Republic of China

National Major Science and Technology Projects of China

Guangzhou Science and Technology Program key projects

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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