Asymmetric synthesis of trifluoromethyl-substituted 3,3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1,3-dipolar cycloaddition reactions-Reference-Cited by-同舟云学术

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Asymmetric synthesis of trifluoromethyl-substituted 3,3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1,3-dipolar cycloaddition reactions

Published:2017 Issue:3 Volume:4 Page:472-482
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Huang Wei-Jie¹²³⁴⁵,Chen Qing⁶⁷⁸⁹¹⁰,Lin Ning⁶⁷⁸⁹¹⁰,Long Xian-Wen¹²³⁴⁵,Pan Wei-Gao⁶⁷⁸⁹,Xiong Yan-Shi¹²³⁴⁵,Weng Jiang¹²³⁴⁵^ORCID,Lu Gui¹²³⁴⁵

Affiliation:

1. Institute of Medicinal Chemistry

2. School of Pharmaceutical Sciences

3. Sun Yat-sen University

4. Guangzhou 510006

5. China

6. College of Pharmacy

7. Guangxi University of Chinese Medicine

8. Nanning 530200

9. People's Republic of China

10. Guangxi Zhuang Yao Medicine Center of Engineering and Technology

Abstract

A series of trifluoromethylated 3,3′-pyrrolidinyl-dispirooxindoles were constructedviaasymmetric [3 + 2] cycloaddition.

Funder

Natural Science Foundation of Guangxi Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/QO/C6QO00723F

Reference55 articles.

1. H. Hiyama , Organofluorine Compounds: Chemistry and Applications, Springer, Berlin, 2000

2. Understanding organofluorine chemistry. An introduction to the C–F bond

3. Applications of Fluorine in Medicinal Chemistry

4. Organic fluorine compounds: a great opportunity for enhanced materials properties

5. The Many Roles for Fluorine in Medicinal Chemistry

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