A synergistic optical strategy for enhanced deep-tumor penetration and therapy in the second near-infrared window

Author:

Wu Di12345ORCID,Chen Xiaohong1234,Zhou Jiajing6789,Chen Yuxuan1234,Wan Tao1234,Wang Yi1234ORCID,Lin Aifu10234,Ruan Yeping111124,Chen Zhong1234,Song Xiangrong1314151617,Fang Wenjun52184ORCID,Duan Hongwei6789ORCID,Ping Yuan1234ORCID

Affiliation:

1. College of Pharmaceutical Sciences

2. Zhejiang University

3. Hangzhou 310058

4. China

5. Department of Chemistry

6. School of Chemical and Biomedical Engineering

7. Nanyang Technological University

8. Singapore 637457

9. Singapore

10. College of Life Sciences

11. Zhejiang Chinese Medical University

12. Hangzhou 310053

13. Department of Critical Care Medicine

14. State Key Laboratory of Biotherapy

15. West China Hospital

16. Sichuan University

17. Chengdu

18. Hangzhou 310028

Abstract

A mesoporous core–shell nanohybrid allows delivery of thermophilic enzymes for stromal depletion and high photothermal conversion efficiency for tumor therapy.

Funder

China Scholarship Council

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

National Basic Research Program of China

Ministry of Education - Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

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