Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens-Reference-Cited by-同舟云学术

Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens

Published:2020 Issue:9 Volume:11 Page:2494-2503
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zheng Zheng¹²³⁴⁵,Liu Haixiang¹²³⁴⁵,Zhai Shaodong⁶⁷⁸⁹¹⁰,Zhang Haoke¹²³⁴⁵^ORCID,Shan Guogang¹²³⁴⁵,Kwok Ryan T. K.¹²³⁴⁵,Ma Chao¹¹¹²¹³¹⁴,Sung Herman H. Y.¹²³⁴⁵,Williams Ian D.¹²³⁴⁵^ORCID,Lam Jacky W. Y.¹²³⁴⁵,Wong Kam Sing¹¹¹²¹³¹⁴,Hu Xianglong⁶⁷⁸⁹¹⁰^ORCID,Tang Ben Zhong¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction

3. Institute for Advanced Study

4. Department of Chemical and Biological Engineering

5. Institute of Molecular Functional Materials

6. MOE Key Laboratory of Laser Life Science

7. Institute of Laser Life Science

8. College of Biophotonics

9. South China Normal University

10. Guangzhou 510631

11. Department of Physics

12. HKUST

13. Kowloon

14. China

Abstract

Mitochondria-targeted photosensitizers with highly efficient singlet oxygen generation, bright near-infrared AIE and good two-photon absorption are obtained through ingenious molecular engineering for cancer cell-selective photodynamic therapy.

Funder

National Natural Science Foundation of China

University Grants Committee

Innovation and Technology Commission

National Basic Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/C9SC06441A

Reference63 articles.