Synthesis of 2-deoxy-d-glucose coated Fe3O4 nanoparticles for application in targeted delivery of the Pt(iv) prodrug of cisplatin – a novel approach in chemotherapy-Reference-Cited by-同舟云学术

Synthesis of 2-deoxy-d-glucose coated Fe3O4 nanoparticles for application in targeted delivery of the Pt(iv) prodrug of cisplatin – a novel approach in chemotherapy

Published:2020 Issue:32 Volume:44 Page:13863-13874
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Sharma K. Shitaljit¹²³⁴,Dubey Akhil K.⁵²³⁴,Koijam Arunkumar S.⁶²³⁴,Kumar Chandan⁶²³⁴,Ballal Anand⁷²³⁴,Mukherjee Sudip⁸⁹³⁴,Phadnis Prasad P.¹²³⁴¹⁰^ORCID,Vatsa Rajesh K.¹²³⁴¹⁰

Affiliation:

1. Chemistry Division

2. Bhabha Atomic Research Centre

3. Mumbai-400 085

4. India

5. Bio-Organic Division

6. Radiopharmaceuticals Division

7. Molecular Biology Division

8. UGC-DAE Consortium for Scientific Research

9. Mumbai Centre

10. Homi Bhabha National Institute

Abstract

Pt(IV) prodrug of cisplatin was loaded on 2DG functionalized silica coated Fe₃O₄ nanoparticles. The formulation alone exhibited biocompatibility whereas Pt(IV) loaded formulation exhibited cytotoxicity comparable with cisplatin.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/C9NJ05989J

Reference139 articles.

1. Platinum Compounds: a New Class of Potent Antitumour Agents

2. Cellular processing of platinum anticancer drugs

3. Carboplatin: the clinical spectrum to date

4. Cisplatin in cancer therapy: Molecular mechanisms of action

5. Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

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