A dual-caged resorufin probe for rapid screening of infections resistant to lactam antibiotics
Author:
Affiliation:
1. Departments of Radiology and Chemistry
2. Molecular Imaging Program at Stanford
3. Stanford University School of Medicine
4. Stanford
5. USA
6. Department of Pathology
7. Clinical Microbiology Laboratory
Abstract
This work reports a dual-caged fluorogenic probe and its demonstration for rapid and sensitive screening of as low as 1000 clinically isolated β-lactamase-expressing bacteria per milliliter urine samples within 2 hours.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC01471D
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