Impact of nano-titanium dioxide extracted from food products on Caco-2 cells using three-phase digestion model

Author:

Jeffcoat Paris12ORCID,Divakarla Shiva Kamini13ORCID,New Elizabeth J.124ORCID,Chrzanowski Wojciech13ORCID

Affiliation:

1. Sydney Nano Institute, The University of Sydney, NSW 2006, Australia

2. School of Chemistry, The University of Sydney, NSW 2006, Australia

3. Sydney Pharmacy School, The University of Sydney, NSW 2006, Australia

4. Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, NSW 2006, Australia

Abstract

This work implicates Zn-mediated cellular processes in the mechanism of toxicological action of TiO2 nanoparticles. Improved understanding of mechanism of toxicological action will inform more proportionate and precautionary regulatory approaches.

Funder

Nano Institute, University of Sydney

Publisher

Royal Society of Chemistry (RSC)

Subject

General Environmental Science,Materials Science (miscellaneous)

Reference80 articles.

1. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles

2. Decreasing Uncertainties in Assessing Environmental Exposure, Risk, and Ecological Implications of Nanomaterials

3. R.Reed , J.Schoepf , M.Masles and P.Westerhoff , Detecting Engineered Nanomaterials in Processed Foods From Australia , Friends of the Earth , 2015

4. Bioinorganic Chemistry of Titanium

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