The antidepressant drug paroxetine as a new lead candidate in schistosome drug discovery-Reference-Cited by-同舟云学术

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The antidepressant drug paroxetine as a new lead candidate in schistosome drug discovery

Published:2016 Issue:6 Volume:7 Page:1176-1182
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Neves Bruno Junior¹²³⁴⁵,Dantas Rafael Ferreira⁶⁷⁸⁹⁵,Senger Mario Roberto⁶⁷⁸⁹⁵,Valente Walter César Góes⁶⁷⁸⁹⁵,Rezende-Neto João de Mello⁶⁷⁸⁹⁵,Chaves Willian Távora⁶⁷⁸⁹⁵,Kamentsky Lee¹⁰¹¹¹²,Carpenter Anne¹⁰¹¹¹²,Silva-Junior Floriano Paes⁶⁷⁸⁹⁵,Andrade Carolina Horta¹²³⁴⁵^ORCID

Affiliation:

1. LabMol – Laboratory for Molecular Modeling and Design

2. Faculdade de Farmácia

3. Universidade Federal de Goiás

4. Goiânia - GO

5. Brazil

6. LaBECFar – Laboratório de Bioquímica Experimental e Computacional de Fármacos

7. Instituto Oswaldo Cruz

8. Fundação Oswaldo Cruz

9. Rio de Janeiro - RJ

10. Imaging Platform, Broad Institute of Massachusetts Institute of Technology and Harvard

11. Cambridge

12. USA

Abstract

Paroxetine is a new anti-schistosomal lead with potent activity against schistosomula and adult life stages of S. mansoni.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação Oswaldo Cruz

National Institutes of Health

Fundação de Amparo à Pesquisa do Estado de Goiás

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C5MD00596E

Reference51 articles.

1. Human schistosomiasis

2. Schistosomiasis

3. Toward the Elimination of Schistosomiasis

4. Human schistosomiasis

5. Praziquantel, a new broad-spectrum antischistosomal agent

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