Cu-catalyzed reductive aminomethylation of 1,3-dienes with <i>N</i>,<i>O</i>-acetals: facile construction of β-chiral amines with quaternary stereocenters-Reference-Cited by-同舟云学术

Cu-catalyzed reductive aminomethylation of 1,3-dienes with N,O-acetals: facile construction of β-chiral amines with quaternary stereocenters

Published:2023 Issue:2 Volume:10 Page:467-472
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Ren Ke¹,Yuan Rong¹,Gui Yong-Yuan¹²,Chen Xiao-Wang³,Min Shi-Yun¹,Wang Bi-Qin¹,Yu Da-Gang³^ORCID

Affiliation:

1. College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, P. R. China

2. Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, P. R. China

3. Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China

Abstract

A copper-catalyzed highly regio- and enantioselective reductive aminomethylation of 1,1-disubstituted 1,3-dienes with N,O-acetals is reported for the first time.

Funder

Sichuan Normal University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO01774A

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