Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling-Reference-Cited by-同舟云学术

Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling

Published:2020 Issue:35 Volume:16 Page:8272-8283
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Jansen Karin A.¹²³⁴⁵^ORCID,Zhmurov Artem⁶⁷⁸⁹¹⁰,Vos Bart E.¹²³⁴¹¹^ORCID,Portale Giuseppe¹²¹³¹⁴¹⁵⁴^ORCID,Hermida-Merino Daniel¹⁶¹⁷¹⁸¹⁹,Litvinov Rustem I.²⁰²¹²²²³²⁴^ORCID,Tutwiler Valerie²⁰²¹²²²³²⁴,Kurniawan Nicholas A.¹²³⁴²⁵^ORCID,Bras Wim¹⁶¹⁷¹⁸¹⁹²⁶^ORCID,Weisel John W.²⁰²¹²²²³²⁴^ORCID,Barsegov Valeri²⁷²⁸²⁹³⁰²⁴,Koenderink Gijsje H.¹²³⁴³¹^ORCID

Affiliation:

1. AMOLF

2. Biological Soft Matter Group

3. Amsterdam

4. The Netherlands

5. UMC Utrecht

6. KTH Royal Institute of Technology

7. Stockholm

8. Sweden

9. Sechenov University

10. Moscow 119991

11. Institute of Cell Biology

12. Macromolecular Chemistry and New Polymeric Materials

13. Zernike Institute for Advanced Materials

14. University of Groningen

15. 9747 AG Groningen

16. Netherlands Organization for Scientific Research (NWO)

17. DUBBLE CRG at the ESRF

18. 38000 Grenoble Cedex

19. France

20. Department of Cell and Developmental Biology

21. Perelman School of Medicine

22. University of Pennsylvania

23. Philadelphia

24. USA

25. Department of Biomedical Engineering and Institute for Complex Molecular Systems

26. Chemical Sciences Division

27. Department of Chemistry

28. University of Massachusetts

29. Lowell

30. 01854

31. Department of Bionanoscience

Abstract

The blood clotting protein fibrin has extraordinary elastomeric properties due to its hierarchical structure. SAXS is combined with computational molecular modeling, providing insight in fibrin elasticity and guidelines for designing new polymers.

Funder

Oak Ridge National Laboratory

American Heart Association

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

National Institutes of Health

National Science Foundation

Kazan Federal University

Perelman School of Medicine, University of Pennsylvania

European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject