Diversely functionalized isoquinolines and their core-embedded heterocyclic frameworks: a privileged scaffold for medicinal chemistry-Reference-Cited by-同舟云学术

Diversely functionalized isoquinolines and their core-embedded heterocyclic frameworks: a privileged scaffold for medicinal chemistry

Published:2023 Issue:12 Volume:14 Page:2509-2534
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Vijayakumar Archana¹,Manod M.¹,Krishna R. Bharath²^ORCID,Mathew Abra¹³,Mohan Chithra¹^ORCID

Affiliation:

1. School of Chemical Sciences, Mahatma Gandhi University, Kottayam 686560, India

2. Institute for Integrated Programmes and Research in Basic Sciences, Mahatma Gandhi University, Kottayam 686560, India

3. Department of Chemistry, Indian Institute of Technology Palakkad, Kerala 678577, India

Abstract

This review will be an essential toolbox for medicinal and bioorganic chemists seeking novel multifunctional hybrid and bioactive N-heterocycles for drug discovery. The work highlights the need for and relevance of unexplored bioisosterism employing isoquinoline-based small-molecules in drug design.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D3MD00248A

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