Enantioselective vinylogous aldol/lactonization cascade reaction between β,γ-unsaturated amides and trifluoromethyl ketones: facile access to chiral trifluoromethyl dihydropyranones
Author:
Affiliation:
1. Key Laboratory for Advanced Materials and Institute of Fine Chemicals
2. School of Chemistry & Molecular Engineering
3. East China University of Science and Technology
4. Shanghai 200237
5. P. R. China
Abstract
β,γ-Unsaturated amides have been used for the first time to react with trifluoromethyl ketones, and chiral α,β-unsaturated δ-lactones bearing a trifluoromethyl group have been constructed in a convenient manner.
Funder
Natural Science Foundation of Shanghai
Fundamental Research Funds for the Central Universities
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01746A
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