Polymorph prediction through observed structural isomorphism leading to a new crystalline form of cannabidiol-Reference-Cited by-同舟云学术

Polymorph prediction through observed structural isomorphism leading to a new crystalline form of cannabidiol

Published:2023 Issue:16 Volume:25 Page:2479-2484
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Straker Hannah E.¹^ORCID,McMillan Lynn¹,Mardiana Lina²³⁴^ORCID,Hebberd Glen R.²^ORCID,Watson Elle²³^ORCID,Waddell Paul G.³^ORCID,Probert Michael R.²³^ORCID,Hall Michael J.²³^ORCID

Affiliation:

1. Jazz Pharmaceuticals, Kent Science Park, Sittingbourne, Kent, ME9 8AG, UK

2. Indicatrix Crystallography Ltd, Bedson Building, Newcastle University, Newcastle upon Tyne, Tyne and Wear, NE1 7RU, UK

3. Chemistry – School of Natural and Environmental Sciences, Bedson Building, Newcastle University, Newcastle upon Tyne, Tyne and Wear, NE1 7RU, UK

4. Department of Chemistry, Universitas Indonesia, Depok, Jawa Barat, 16424, Indonesia

Abstract

A new polymorph of cannabidiol (CBD, form 2), a bioactive phytocannabinoid, was discovered via high-throughput crystallisation. CBD form 2 fits within a series of crystal structures of CBD C-5′ homologues, forming a set of homologous isomorphs.

Funder

Lembaga Pengelola Dana Pendidikan

Newcastle University

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CE/D3CE00041A

Reference23 articles.

1. Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects

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