Neuroprotective effects of salidroside against 6-OHDA-induced oxidative stress in PC12 cells-Reference-Cited by-同舟云学术

Neuroprotective effects of salidroside against 6-OHDA-induced oxidative stress in PC12 cells

Published:2023 Issue:29 Volume:47 Page:14039-14045
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Li Minyan¹,Wang Sha¹,Fu Chunmei¹,Chen Hongyu¹,Su Yuxia²,Wu Peng¹,Yan Xinhao¹^ORCID,Gao Juanjuan³

Affiliation:

1. Hanzhong Key Laboratory of Clinical Molecular Biology, Hanzhong Vocational and Technical College, Hanzhong 723002, P. R. China

2. Department of Pharmacy, Hanzhong People's Hospital, Hanzhong 723000, P. R. China

3. Department of Neurology, Hanzhong People's Hospital, Hanzhong 723000, P. R. China

Abstract

Neuroprotective effects of salidroside (Sal) in PC12 cells against oxidative stress induced by 6-hydroxydopamine (6-OHDA). Sal scavenges reactive oxygen species (ROS), enhances antioxidant enzyme activity (SOD, CAT, GPX4), and reduces α-synuclein (α-syn) accumulation.

Funder

Shanxi Provincial Education Department

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ01746J

Reference32 articles.

1. Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier

2. Parkinson disease

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4. Approaches for Reactive Oxygen Species and Oxidative Stress Quantification in Epilepsy

5. Age-dependent alpha-synuclein accumulation and aggregation in the colon of a transgenic mouse model of Parkinson’s disease

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