Discovery of novel 1,2,4-triazole tethered β-hydroxy sulfides as bacterial tyrosinase inhibitors: synthesis and biophysical evaluation through <i>in vitro</i> and <i>in silico</i> approaches-Reference-Cited by-同舟云学术

Discovery of novel 1,2,4-triazole tethered β-hydroxy sulfides as bacterial tyrosinase inhibitors: synthesis and biophysical evaluation through in vitro and in silico approaches

Published:2024 Issue:22 Volume:14 Page:15419-15430
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Saeed Sadaf¹,Saif Muhammad Jawwad²^ORCID,Zahoor Ameer Fawad¹^ORCID,Tabassum Hina³,Kamal Shagufta⁴,Faisal Shah⁵^ORCID,Ashraf Rabia¹,Khan Samreen Gul¹,Nazeer Usman⁶,Irfan Ali¹^ORCID,Bhat Mashooq Ahmad⁷^ORCID

Affiliation:

1. Department of Chemistry, Government College University Faisalabad, 38000-Faisalabad, Pakistan

2. Department of Applied Chemistry, Government College University Faisalabad, 38000-Faisalabad, Pakistan

3. London Metropolitan University, 166-220 Holloway Road, London N7 8DB, UK

4. Department of Biochemistry, Government College University Faisalabad, 38000-Faisalabad, Pakistan

5. Department of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan

6. Department of Chemistry, University of Houston, 3585 Cullen Boulevard, Texas 77204-5003, USA

7. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia

Abstract

This study reports the bacterial tyrosinase inhibiting potency of a series of novel 1,2,4-triazole-tethered β-hydroxy sulfide scaffolds 11(a–h), synthesized in good yields (69–90%).

Funder

King Saud University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA01252F

Reference57 articles.

1. Synthesis and biological activity of hydroxy substituted phenyl-benzo[d]thiazole analogues for antityrosinase activity in B16 cells

2. Pyocyanin as anti-tyrosinase and anti tinea corporis: A novel treatment study

3. Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries

4. Natural, semisynthetic and synthetic tyrosinase inhibitors

5. Design and synthesis of aloe-emodin derivatives as potent anti-tyrosinase, antibacterial and anti-inflammatory agents

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bacterial tyrosinases and their inhibitors;The Enzymes;2024