Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles
Author:
Affiliation:
1. Institute of Materials and Environmental Chemistry
2. Research Centre for Natural Sciences
3. Budapest
4. Hungary
5. Research Institute of Biomolecular and Chemical Engineering
6. Institute of Enzymology
Abstract
Interferon-beta-1a (IFN-β-1a) can diminish the symptoms of relapsing-remitting multiple sclerosis.
Funder
Gedeon Richter
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA09928J
Reference34 articles.
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4. Recombinant Interferon-??-1a*
5. N-Terminally PEGylated Human Interferon-β-1a with Improved Pharmacokinetic Properties and in Vivo Efficacy in a Melanoma Angiogenesis Model
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