Significance of the RBD mutations in the SARS-CoV-2 omicron: from spike opening to antibody escape and cell attachment-Reference-Cited by-同舟云学术

Significance of the RBD mutations in the SARS-CoV-2 omicron: from spike opening to antibody escape and cell attachment

Published:2022 Issue:16 Volume:24 Page:9123-9129
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Hossen Md Lokman¹^ORCID,Baral Prabin¹,Sharma Tej¹,Gerstman Bernard¹²,Chapagain Prem¹²^ORCID

Affiliation:

1. Department of Physics, Florida International University, Miami, FL 33199, USA

2. Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, USA

Abstract

We computationally investigated the role of the omicron RBD mutations on its structure and interactions with the surrounding domains in the spike trimer as well as with ACE2.

Funder

National Science Foundation

University Graduate School, Florida International University

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CP/D2CP00169A

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