Design, synthesis, biological evaluation and molecular docking studies of quinoline-anthranilic acid hybrids as potent anti-inflammatory drugs-Reference-Cited by-同舟云学术

Design, synthesis, biological evaluation and molecular docking studies of quinoline-anthranilic acid hybrids as potent anti-inflammatory drugs

Published:2024 Issue:18 Volume:22 Page:3708-3724
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Siddique Sidra¹,Hussain Khalid¹²,Shehzadi Naureen¹,Arshad Muhammad³^ORCID,Arshad Muhammad Nadeem⁴,Iftikhar Sadaf⁵,Saghir Farhat¹²,Shaukat Ayisha¹,Sarfraz Muhammad³^ORCID,Ahmed Nisar⁶^ORCID

Affiliation:

1. Punjab University College of Pharmacy, University of the Punjab, Allama Iqbal Campus, Lahore, Pakistan

2. Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan

3. Institute of Chemistry, The Islamia University of Bahawalpur, Bahawalpur-63100, Pakistan

4. Chemistry Department, Faculty of Science, and Center of Excellence for Advanced Material Research, King Abdulaziz University, Jeddah 21589, P.O. Box 80203, Saudi Arabia

5. Department of Pharmacy, University of South Asia, Lahore, Pakistan

6. School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff, CF10 3AT, UK

Abstract

Despite the high global prevalence, rheumatoid arthritis lacks a satisfactory treatment.

Funder

Higher Education Commision, Pakistan

Cardiff University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00040D

Reference71 articles.

1. Inhibition of Tpl2 kinase and TNFα production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis

2. Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications

3. Mechanism of action of hydroxychloroquine as an antirheumatic drug

4. The mechanisms of hydroxychloroquine in rheumatoid arthritis treatment: Inhibition of dendritic cell functions via Toll like receptor 9 signaling

5. Hydroxychloroquine decreases Th17-related cytokines in systemic lupus erythematosus and rheumatoid arthritis patients

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