Synthesis of hydrophobically modified berberine derivatives with high anticancer activity through modulation of the MAPK pathway-Reference-Cited by-同舟云学术

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Synthesis of hydrophobically modified berberine derivatives with high anticancer activity through modulation of the MAPK pathway

Published:2020 Issue:33 Volume:44 Page:14024-14034
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Wang Lizhen¹²³⁴⁵^ORCID,Yang Xueliang¹²³⁴⁵,Li Xiaobin¹²³⁴⁵,Stoika Rostyslav⁶⁷⁸⁹¹⁰,Wang Xue¹²³⁴⁵,Lin Houwen¹¹¹²¹³¹⁴³^ORCID,Ma Yukui¹⁵¹⁶¹⁷³,Wang Rongchun¹²³⁴⁵^ORCID,Liu Kechun¹²³⁴⁵

Affiliation:

1. Biology Institute, Qilu University of Technology (Shandong Academy of Sciences)

2. Jinan 250353

3. China

4. Engineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province

5. Qilu University of Technology (Shandong Academy of Sciences)

6. Department of Regulation of Cell Proliferation and Apoptosis

7. Institute of Cell Biology

8. National Academy of Sciences of Ukraine

9. Lviv

10. Ukraine

11. Research Center for Marine Drugs

12. State Key Laboratory of Oncogenes and Related Genes

13. Shanghai Jiao Tong University

14. Shanghai

15. Shandong Provincial Key Laboratory of Chemical Drugs

16. Shandong Academy of Pharmaceutical Sciences

17. 250101 Jinan

Abstract

Linoleic acid-modified berberine derivative induces apoptosis of A549 cells and affects the expression of proteins associated with the MAPK pathway.

Funder

Shandong Academy of Sciences

Key Technology Research and Development Program of Shandong

Taishan Scholar Project of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ01645D

Reference83 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

2. Design, synthesis of 4,5-diazafluorene derivatives and their anticancer activity via targeting telomeric DNA G-quadruplex

3. New strategies for targeting the hypoxic tumour microenvironment in breast cancer

4. New Strategies in the Treatment of Ovarian Cancer: Current Clinical Perspectives and Future Potential

5. New strategies for cancer gene therapy: Progress and opportunities

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4. A Comparative Study of the Inhibitory Action of Berberine Derivatives on the Recombinant Protein FtsZ of E. coli;International Journal of Molecular Sciences;2023-03-16

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