Reductive cleavage of the N–O bond: elemental sulfur-mediated conversion of N-alkoxyamides to amides-Reference-Cited by-同舟云学术

Reductive cleavage of the N–O bond: elemental sulfur-mediated conversion of N-alkoxyamides to amides

Published:2019 Issue:3 Volume:6 Page:347-351
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Senlin¹²³⁴⁵,Zhao Xue¹²³⁴⁵,Zhang-Negrerie Daisy¹²³⁴⁵,Du Yunfei¹²³⁴⁵^ORCID

Affiliation:

1. Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency

2. School of Pharmaceutical Science and Technology

3. Tianjin University

4. Tianjin 300072

5. China

Abstract

By treating with elemental sulfur in the presence of DABCO in DMSO, a variety of N-alkoxyamides were readily converted to amides in satisfactory to excellent yields via a metal-free reductive cleavage of the N–O bond.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C8QO01052H

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