Switching the aptamer attachment geometry can dramatically alter the signalling and performance of electrochemical aptamer-based sensors-Reference-Cited by-同舟云学术

Switching the aptamer attachment geometry can dramatically alter the signalling and performance of electrochemical aptamer-based sensors

Published:2021 Issue:88 Volume:57 Page:11693-11696
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Chamorro-Garcia Alejandro¹²^ORCID,Ortega Gabriel¹³⁴^ORCID,Mariottini Davide²^ORCID,Green Joshua⁴^ORCID,Ricci Francesco²^ORCID,Plaxco Kevin W.¹⁴^ORCID

Affiliation:

1. Center for Bioengineering, University of California Santa Barbara, Santa Barbara, CA 93106, USA

2. Dipartimento di Scienze e Tecnologie Chimiche, University of Rome, Tor Vergata, Via della Ricerca Scientifica, Rome 00133, Italy

3. Precision Medicine and Metabolism Laboratory, CIC bioGUNE, Basque Research and Technology Alliance, Parque Tecnológico de Bizkaia, Derio, Spain

4. Department of Chemistry and Biochemistry, University of California Santa Barbara (UCSB), Santa Barbara, CA 93106, USA

Abstract

Switching which termini the redox reporter and surface-anchoring thiol are on, in electrochemical aptamer-based sensors, significantly alters their performance.

Funder

Foundation for the National Institutes of Health

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC04557A

Reference42 articles.

1. Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA

2. Label-Free Electronic Detection of Thrombin in Blood Serum by Using an Aptamer-Based Sensor

3. Preparation of electrode-immobilized, redox-modified oligonucleotides for electrochemical DNA and aptamer-based sensing

4. Reagentless, Structure-Switching, Electrochemical Aptamer-Based Sensors

5. Continuous, Real-Time Monitoring of Cocaine in Undiluted Blood Serum via a Microfluidic, Electrochemical Aptamer-Based Sensor

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