Combining a hybrid chip and tube microfluidic system with fluorescent molecularly imprinted polymer (MIP) core–shell particles for the derivatisation, extraction, and detection of peptides with N-terminating phosphorylated tyrosine-Reference-Cited by-同舟云学术

Combining a hybrid chip and tube microfluidic system with fluorescent molecularly imprinted polymer (MIP) core–shell particles for the derivatisation, extraction, and detection of peptides with N-terminating phosphorylated tyrosine

Published:2023 Issue:3 Volume:23 Page:466-474
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Burnage Samual C.¹^ORCID,Bell Jérémy¹^ORCID,Wan Wei¹,Kislenko Evgeniia¹^ORCID,Rurack Knut¹^ORCID

Affiliation:

1. Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstätter-Str. 11, 12489 Berlin, Germany

Abstract

A microfluidic ratiometric detection scheme using silica nanoparticles coated with a “light-up” fluorescent molecularly imprinted polymer allows selective rapid assaying of pY-terminating peptides after in-tube/on-chip derivatisation and extraction.

Funder

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D2LC00955B

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