Development of lacto-series ganglioside fluorescent probe using late-stage sialylation and behavior analysis with single-molecule imaging-Reference-Cited by-同舟云学术

Development of lacto-series ganglioside fluorescent probe using late-stage sialylation and behavior analysis with single-molecule imaging

Published:2022 Issue:7 Volume:3 Page:868-885
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Takahashi Maina¹²,Komura Naoko³^ORCID,Yoshida Yukako²,Yamaguchi Eriko³,Hasegawa Ami²,Tanaka Hide-Nori¹²³,Imamura Akihiro¹²³^ORCID,Ishida Hideharu¹²³⁴,Suzuki Kenichi G. N.¹²³,Ando Hiromune¹²³^ORCID

Affiliation:

1. The United Graduate School of Agricultural Science, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan

2. Department of Applied Bioorganic Chemistry, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan

3. Institute for Glyco-core Research (iGCORE), Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan

4. Center for Highly Advanced Integration of Nano and Life Sciences (G-CHAIN), Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan

Abstract

A lacto-series ganglioside fluorescent probe was synthesized via direct α-sialylation of glycolipid. Single-molecule imaging revealed interactions between the ganglioside and a major raft molecule.

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Takeda Science Foundation

Uehara Memorial Foundation

Mizutani Foundation for Glycoscience

Suntory Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

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