Diastereoselective addition of anisoles to N-tert-butanesulfinyl imines via four-membered lithium cycles

Author:

Reddy Leleti Rajender1234ORCID,Kotturi Sharadsrikar1234,Waman Yogesh1234,Patel Chirag1234,Patwa Aditya1234,Shenoy Rajesh1234

Affiliation:

1. Piramal Discovery Solutions

2. Pharmaceutical Special Economic Zone

3. Ahmedabad

4. India

Abstract

A highly regio- and diastereo-selective ortho-lithiation/addition of anisoles to N-tert-butanesulfinyl imines resulting in the selective formation of chiral α-branched amines is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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