Enantioselective hydrophosphonylation of N-Boc imines using chiral guanidine–thiourea catalysts-Reference-Cited by-同舟云学术

Enantioselective hydrophosphonylation of N-Boc imines using chiral guanidine–thiourea catalysts

Published:2021 Issue:48 Volume:19 Page:10560-10564
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Chassillan Louis¹²,Yamashita Yasuhiro²^ORCID,Yoo Woo-Jin²^ORCID,Toffano Martial¹^ORCID,Guillot Régis¹^ORCID,Kobayashi Shū²^ORCID,Vo-Thanh Giang¹^ORCID

Affiliation:

1. Université Paris-Saclay, Institut de Chimie Moléculaire et des Matériaux d'Orsay, 91405 Orsay, France

2. Department of Chemistry, School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan

Abstract

The synthesis of new guanidine-thiourea catalysts and their use for the formation of α-amino phosphonate by asymmetric hydrophosphonylation of N-Boc aldimines under batch and continous-flow conditions is described.

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Centre National de la Recherche Scientifique

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01953H

Reference48 articles.

1. The chemistry and biology of guanidine natural products