Fibrinogen aptamer functionalized gold-coated iron-oxide nanoparticles for targeted imaging of thrombi-Reference-Cited by-同舟云学术

Fibrinogen aptamer functionalized gold-coated iron-oxide nanoparticles for targeted imaging of thrombi

Published:2022 Issue:17 Volume:58 Page:2870-2873
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Koudrina Anna¹,Chartrand Celine¹,Cron Greg O²³⁴,O’Brien Jonathan⁴,Tsai Eve C²³⁴,DeRosa Maria C¹^ORCID

Affiliation:

1. Department of Chemistry, Carleton University, 1125 Colonel By Dr, Ottawa, ON K1S 5B6, Canada

2. Ottawa Hospital Research Institute, 1053 Carling Ave, Ottawa, ON K1Y 4E9, Canada

3. Faculty of Medicine, University of Ottawa, 75 Laurier Ave. E, Ottawa, ON K1N 6N5, Canada

4. The Ottawa Hospital, 501 Smyth Rd, Ottawa, ON K1H 8L6, Canada

Abstract

Targeting of molecular constituents of thrombi with aptamer functionalized core–shell nanoparticles (CSN) allowed for high resolution clot delineation in T2-weighted magnetic resonance imaging.

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D1CC03817F

Reference31 articles.

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4. Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers

5. EP-2104R: A Fibrin-Specific Gadolinium-Based MRI Contrast Agent for Detection of Thrombus

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