Synthesis, cytotoxicity and anti-inflammatory activity of rhamnose-containing ursolic and betulinic acid saponins-Reference-Cited by-同舟云学术

Synthesis, cytotoxicity and anti-inflammatory activity of rhamnose-containing ursolic and betulinic acid saponins

Published:2019 Issue:68 Volume:9 Page:39743-39757
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sylla Balla¹²³⁴⁵,Lavoie Serge⁶⁷⁸,Legault Jean¹²³⁴⁵,Gauthier Charles¹²³⁴⁵^ORCID,Pichette André¹²³⁴⁵

Affiliation:

1. Centre de Recherche sur La Boréalie (CREB)

2. Chaire de Recherche sur Les Agents Anticancéreux D'origine Naturelle

3. Laboratoire LASEVE

4. Département des Sciences Fondamentales

5. Université du Québec à Chicoutimi

6. Institut des Sciences de la Forêt Tempérée

7. Université du Québec en Outaouais

8. Canada

Abstract

Rhamnose-containing saponins featuring betulinic and ursolic acid as aglycones were synthesized using both Schmidt's normal and inverse procedures. Some of these synthetic saponins exhibited selective cytotoxic and/or anti-inflammatory activities.

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

Fonds de Recherche du Québec – Santé

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA09389C

Reference39 articles.

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