Binaphthyl–prolinol chiral ligands: design and their application in enantioselective arylation of aromatic aldehydes-Reference-Cited by-同舟云学术

Binaphthyl–prolinol chiral ligands: design and their application in enantioselective arylation of aromatic aldehydes

Published:2021 Issue:16 Volume:19 Page:3644-3655
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Yao Chao¹²³⁴⁵,Chen Yaoqi¹²³⁴⁵,Sun Ruize¹²³⁴⁵,Wang Chao¹²³⁴⁵,Huang Yue¹²³⁴⁵,Li Lin¹²³⁴⁵,Li Yue-Ming¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Medicinal Chemical Biology

2. College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research

3. Nankai University

4. Tianjin

5. People's Republic of China

Abstract

Binaphthyl–prolinol chiral ligands were designed and evaluated with enantioselective arylation of aromatic aldehydes and related reactions. Under optimized conditions, the desired products could be obtained in high yields with up to 99% ee's.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00289A

Reference46 articles.

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