Effect of the phosphorylation structure in casein phosphopeptides on the proliferation, differentiation, and mineralization of osteoblasts and its mechanism-Reference-Cited by-同舟云学术

Effect of the phosphorylation structure in casein phosphopeptides on the proliferation, differentiation, and mineralization of osteoblasts and its mechanism

Published:2023 Issue:22 Volume:14 Page:10107-10118
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhong Wanying¹,He Jian²,Huang Wen¹,Yin Guangling²,Liu Guo¹,Cao Yong¹^ORCID,Miao Jianyin¹^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, Guangzhou, Guangdong 510642, China

2. BYHEALTH Institute of Nutrition & Health, No. 3 Kehui 3rd Street, No. 99 Kexue Avenue Central, Huangpu District, Guangzhou, Guangdong Province 510663, China

Abstract

Our study demonstrated that the highly phosphorylated casein phosphopeptide (residues 1-25) P5 efficiently promoted proliferation, differentiation, and mineralisation of MC3T3-E1 cells, and its phosphorylation structure also efficiently induced EGFR binding.

Funder

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO03125J

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