Concise synthesis of succinimide-fused 1,3-cyclohexadienes <i>via</i> Co-catalyzed [2 + 2 + 2] cycloaddition of 1,6-diynes and maleimides-Reference-Cited by-同舟云学术

Concise synthesis of succinimide-fused 1,3-cyclohexadienes via Co-catalyzed [2 + 2 + 2] cycloaddition of 1,6-diynes and maleimides

Published:2024 Issue:11 Volume:11 Page:3257-3262
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Cen Kaili¹,Zhai Ziyi¹,Liu Yuan²,Wei Jiahao³,Ouyang Mixia¹,He Guojun¹,Huang Shuyu¹,Zhao Feng⁴^ORCID,Cai Jinhui¹^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, Hunan, China

2. Chuanshan College University of South China, University of China, Henyang 421001, Hunan, China

3. School of Pharmaceutical Science, University of South China, Henyang 421001, Hunan, China

4. Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, Hunan, China

Abstract

This work has realized a facile assembly of succinimide-fused 1,3-cyclohexadienes via Co-catalyzed [2 + 2 + 2] cycloaddition of 1,6-diynes to maleimides. Furthermore, the oxidation of succinimide-fused 1,3-cyclohexadienes was carried out under I2/MeONa.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00435C

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