Methylene-bridged dimeric natural products involving one-carbon unit in biosynthesis

Author:

Fan Yaqin1ORCID,Shen Jingjing2,Liu Zhi2,Xia Kunyu2,Zhu Weiming23ORCID,Fu Peng23ORCID

Affiliation:

1. Shandong Provincial Key Laboratory of Applied Mycology, School of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China

2. Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China

3. Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266237, China

Abstract

This review summarizes the methylene-bridged dimeric natural products involving one-carbon unit in biosynthesis, including their structures, biological activities, synthetic methods, and formation mechanisms.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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