Structural-model-based genome mining can efficiently discover novel non-canonical terpene synthases hidden in genomes of diverse species-Reference-Cited by-同舟云学术

Structural-model-based genome mining can efficiently discover novel non-canonical terpene synthases hidden in genomes of diverse species

Published:2024 Issue:27 Volume:15 Page:10402-10407
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Abe Tohru¹^ORCID,Shiratori Haruna¹,Kashiwazaki Kosuke²,Hiasa Kazuma³,Ueda Daijiro¹^ORCID,Taniguchi Tohru⁴^ORCID,Sato Hajime³⁵^ORCID,Abe Takashi²,Sato Tsutomu¹^ORCID

Affiliation:

1. Department of Life and Food Sciences, Graduate School of Science and Technology, Niigata University, Ikarashi 2-8050, Nishi-ku, Niigata, 950-2181, Japan

2. Department of Electrical and Information Engineering, Graduate School of Science and Technology, Niigata University, Ikarashi 2-8050, Nishi-ku, Niigata, 950-2181, Japan

3. Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, 4-4-37 Takeda, Kofu, Yamanashi 400-8510, Japan

4. Frontier Research Center for Advanced Material and Life Science, Faculty of Advanced Life Science, Hokkaido University, North 21 West 11, Sapporo 001-0021, Japan

5. PRESTO, Japan Science and Technology Agency, Kawaguchi, Saitama 332-0012, Japan

Abstract

Non-canonical terpene synthases with primary sequences that are unrecognizable as canonical terpene synthases could be discovered through structural-model-based genome mining.

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D4SC01381F

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5. Bacterial terpene cyclases