Synthesis of 2-arylated thiadiazolopyrimidones by Suzuki–Miyaura cross-coupling: a new class of nucleotide pyrophosphatase (NPPs) inhibitors-Reference-Cited by-同舟云学术

Synthesis of 2-arylated thiadiazolopyrimidones by Suzuki–Miyaura cross-coupling: a new class of nucleotide pyrophosphatase (NPPs) inhibitors

Published:2016 Issue:109 Volume:6 Page:107556-107571
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jafari Behzad¹²³⁴,Yelibayeva Nazym¹²³⁴⁵,Ospanov Meirambek¹²³⁴⁵,Ejaz Syeda Abida⁶⁷⁸⁹,Afzal Saira⁶⁷⁸⁹,Khan Shafi Ullah⁶⁷⁸⁹,Abilov Zharylkasyn A.⁵¹⁰¹¹,Turmukhanova Mirgul Z.⁵¹⁰¹¹,Kalugin Sergey N.⁵¹⁰¹¹,Safarov Sayfidin¹²¹³¹⁴¹⁵,Lecka Joanna¹⁶¹⁷¹⁸¹⁹²⁰,Sévigny Jean¹⁶¹⁷¹⁸¹⁹²⁰,Rahman Qamar¹²³⁴²¹,Ehlers Peter¹²³⁴²²,Iqbal Jamshed⁶⁷⁸⁹,Langer Peter¹²³⁴²²

Affiliation:

1. Institut für Chemie

2. Universität Rostock

3. 18059 Rostock

4. Germany

5. Al-Farabi Kazakh National University

6. Centre for Advanced Drug Research

7. COMSATS Institute of Information Technology

8. Abbottabad

9. Pakistan

10. 050040 Almaty

11. Kazakhstan

12. Institute of Chemistry

13. Tajikistan Academy of Sciences

14. Dushanbe

15. 734063 Tajikistan

16. Département de microbiologie-infectiologie et d'immunologie

17. Faculté de Médecine

18. Université Laval

19. Québec

20. Canada

21. Amity University

22. Leibniz Institut für Katalyse an der Universität Rostock e.V. (LIKAT)

Abstract

Over expression of nucleotide pyrophosphatase (NPPs) activity is associated with chondrocalcinosis, osteoarthritis, type 2 diabetes, neurodegenerative diseases, allergies and cancer metastasis.

Funder

Organisation for the Prohibition of Chemical Weapons

German Academic Exchange Service

Higher Education Commission, Pakistan

Canadian Institutes of Health Research

Fonds de Recherche du Québec - Santé

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA22750C