An ESIPT fluorescent probe sensitive to protein α-helix structures
Author:
Affiliation:
1. Key Laboratory of Pesticide & Chemical Biology
2. Ministry of Education
3. School of Chemistry
4. Central China Normal University
5. Chemistry Building
Abstract
A benzazole derivative,1, was observed to undergo the excited-state intramolecular proton transfer (ESIPT) process with α-helical proteins. The cell images showed a difference in the staining of normal and cancerous prostate cells by1, which might be due to the different membrane protein levels.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00405A
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5. Steady-State and Time-Resolved Study of the Proton-Transfer Fluorescence of 4-Hydroxy-5-azaphenanthrene in Model Solvents and in Complexes with Human Serum Albumin
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