A PEGylated N-heterocyclic carbene-gold(i) complex: an efficient catalyst for cyclization reaction in water

Author:

Lin Bijin12342,Zhang Xumu2564ORCID,Zhou Cong-Ying1234,Che Chi-Ming12342ORCID

Affiliation:

1. State Key Laboratory of Synthetic Chemistry

2. Department of Chemistry

3. The University of Hong Kong

4. China

5. Southern University of Science and Technology

6. Shenzhen 518000

Abstract

A recyclable, PEGylated N-heterocyclic carbene(NHC)–gold(i) catalyst was synthesized, which exhibited high reactivity and regio-selectivity in the cyclization of alkynoic acids and cascade reaction of tryptamine and alkynoic acids in water.

Funder

National Natural Science Foundation of China

Innovation and Technology Commission

Research Grants Council, University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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