Advances in targeting and heterologous expression of genes involved in the synthesis of fungal secondary metabolites

Author:

Qiao Yun-Ming12345,Yu Rui-Lin12345,Zhu Ping12345ORCID

Affiliation:

1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines

2. NHC Key Laboratory of Biosynthesis of Natural Products

3. CAMS Key Laboratory of Enzyme and Biocatalysis of Natural Drugs

4. Institute of Materia Medica

5. Chinese Academy of Medical Sciences

Abstract

Gene targeting involves integration of foreign DNA into the fungal genome by several strategies including Agrobacterium tumefaciens-mediated transformation (ATMT).

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Chinese Academy of Meteorological Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference99 articles.

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3. Metabolic Pathway Gene Clusters in Filamentous Fungi

4. Ergot alkaloids: structure diversity, biosynthetic gene clusters and functional proof of biosynthetic genes

5. FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes

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