Antiangiogenic platinum through glycan targeting-Reference-Cited by-同舟云学术

Antiangiogenic platinum through glycan targeting

Published:2017 Issue:1 Volume:8 Page:241-252
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Peterson Erica J.¹²³⁴⁵,Daniel A. Gerard¹²³⁴⁵,Katner Samantha J.¹²³⁴⁵,Bohlmann Lisa⁶⁷⁸⁹¹⁰,Chang Chih-Wei⁶⁷⁸⁹¹⁰,Bezos Anna¹¹¹²¹³¹⁰,Parish Christopher R.¹¹¹²¹³¹⁰,von Itzstein Mark⁶⁷⁸⁹¹⁰,Berners-Price Susan J.⁶⁷⁸⁹¹⁰,Farrell Nicholas P.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Virginia Commonwealth University

3. Richmond VA 23284

4. USA

5. The Massey Cancer Center

6. Institute for Glycomics

7. Griffith University

8. Gold Coast Campus

9. Southport

10. Australia

11. John Curtin School of Medical Research

12. The Australian National University

13. Canberra

Abstract

The high affinity of highly charged polynuclear platinum complexes for glycans such as heparan sulfate results in modulation of the biomolecule signaling functions leading to inhibition of angiogenesis.

Funder

National Institutes of Health

Australian Research Council

National Health and Medical Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC02515C

Reference56 articles.

1. Heparin/Heparan Sulfate Proteoglycans Glycomic Interactome in Angiogenesis: Biological Implications and Therapeutical Use