Facile construction of highly luminescent and biocompatible gold nanoclusters by shell rigidification for two-photon pH-edited cytoplasmic and in vivo imaging

Author:

Peng Yaowei1,Gao Lu1,Pidamaimaiti Guligena2,Zhao Dan1,Zhang Lumin3,Yin Guowei4,Wang Fu1ORCID

Affiliation:

1. School of Biomedical Engineering, State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants, Shanghai Jiao Tong University, Shanghai 200240, China

2. Key Laboratory of Pollutant Chemistry and Environmental Treatment, School of Chemistry and Environmental Science, Yili Normal University, Yining 835000, China

3. Department of Chemistry and Biochemistry, The Ohio State University 151 W. Woodruff Ave., Columbus, OH 43210, USA

4. Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China

Abstract

The biocompatible and highly luminescent PVP-AuNCs were synthesized by using a facile mixture of HAuCl4, ATT and PVP solutions, which can be used for intracellular pH response and in vivo two-photon fluorescence imaging.

Funder

Chinese Academy of Sciences

Science and Technology Foundation of Shenzhen City

Science, Technology and Innovation Commission of Shenzhen Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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