Zinc(<scp>ii</scp>)-mediated stereoselective construction of 1,2-<i>cis</i> 2-azido-2-deoxy glycosidic linkage: assembly of <i>Acinetobacter baumannii</i> K48 capsular pentasaccharide derivative-Reference-Cited by-同舟云学术

Zinc(ii)-mediated stereoselective construction of 1,2-cis 2-azido-2-deoxy glycosidic linkage: assembly of Acinetobacter baumannii K48 capsular pentasaccharide derivative

Published:2024 Issue:32 Volume:15 Page:12889-12899
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zhao Xiaoya¹,Ding Han²^ORCID,Guo Aoxin²,Zhong Xuemei¹,Zhou Siai¹,Wang Guoqing¹,Liu Yuhua³,Ishiwata Akihiro⁴^ORCID,Tanaka Katsunori⁴⁵^ORCID,Cai Hui¹,Liu Xue-Wei²^ORCID,Ding Feiqing¹^ORCID

Affiliation:

1. School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China

2. School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637371, Singapore

3. School of Physics and Electronic Engineering, Guangzhou University, Guangzhou 510006, China

4. RIKEN Cluster for Pioneering Research, Wako, Saitama 3510198, Japan

5. Department of Chemical Science and Engineering, Tokyo Institute of Technology, Tokyo, Japan

Abstract

The capsular polysaccharide (CPS) is a major virulence factor of the pathogenic Acinetobacter baumannii and a promising target for vaccine development.

Funder

Basic and Applied Basic Research Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D4SC03449J

Reference37 articles.

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2. Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges

3. Mapping Global Prevalence of Acinetobacter baumannii and Recent Vaccine Development to Tackle It

4. Stereoselective Synthesis of the O‐antigen of A. baumannii ATCC 17961 Using Long‐Range Levulinoyl Group Participation

5. Synthesis of the Tetrasaccharide Repeating Unit from Acinetobacter baumannii Serogroup O18 Capitalizing on Phosphorus-Containing Leaving Groups