Palladium-catalyzed C(sp3)–Si cross-coupling silylation of benzyl halides with hydrosilanes

Author:

Zhou Xiao-Hua1,Zhu Jun-Hui1,Song Guang-Ao1,Jiang Xin-Li1,Fang Xiao-Jun1,Xu Zheng1,Xu Li-Wen123ORCID

Affiliation:

1. Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, and Key Laboratory of Organosilicon Material Technology of Zhejiang Province, College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 311121, P. R. China

2. State Key Laboratory for Oxo Synthesis and Selective Oxidation, Suzhou Research Institute (SRI), Lanzhou Institute of Chemical Physics (LICP), University of the Chinese Academy of Sciences (UCAS), Lanzhou 730000, P. R. China

3. Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province, School of Science, Westlake University, P. R. China

Abstract

An unprecedent and chemoselective Si–C(sp3) bond-forming cross-coupling silylation of benzyl halides with hydrosilanes has been established by palladium catalysis and B(C6F5)3 for the facile synthesis of functional benzyl silanes with good yields.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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