Getting a molecular grip on the half-lives of iminothioindoxyl photoswitches

Author:

Boëtius Melody E.123,Hoorens Mark W. H.12,Ošťadnický Martin4,Laurent Adèle D.5ORCID,di Donato Mariangela67ORCID,van Wingaarden Aldo C. A.2,Hilbers Michiel F.8ORCID,Feringa Ben L.2ORCID,Buma Wybren Jan89ORCID,Medveď Miroslav1011ORCID,Szymanski Wiktor123ORCID

Affiliation:

1. Department of Radiology, Medical Imaging Center, University Medical Center Groningen, Hanzeplein 1, 9713GZ Groningen, The Netherlands

2. Center for Systems Chemistry, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 7, Groningen, The Netherlands

3. Department of Medicinal Chemistry, Photopharmacology and Imaging, Groningen Research Institute of Pharmacy, University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands

4. Faculty of Natural Sciences, Comenius University, Ilkovičova 6, SK-842 15 Bratislava, Slovak Republic

5. Nantes Université, CNRS CEISAM, UMR 6230, F-44000 Nantes, France

6. LENS, European Laboratory for Non-Linear Spectroscopy, 50019 Sesto Fiorentino, FI, Italy

7. CNR-ICCOM, via Madonna del Piano 10, 50019, Sesto Fiorentino (FI), Italy

8. Van't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands

9. Institute for Molecules and Materials, FELIX Laboratory, Radboud University, Toernooiveld 7c, 6525 ED Nijmegen, The Netherlands

10. Faculty of Natural Sciences, Department of Chemistry, Matej Bel University, Tajovského 40, SK-97400 Banská Bystrica, Slovak Republic

11. Regional Centre of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute (CATRIN), Palacky University Olomouc, Křížkovského 511/8, 77900 Olomouc, Czech Republic

Abstract

Molecular engineering of an ITI photoswitch, supported by DFT calculations and advanced spectroscopy, allows the half-life of its unstable state to be boosted to the levels needed for biological applications.

Funder

Agentúra na Podporu Výskumu a Vývoja

Ministerstvo Školství, Mládeže a Tělovýchovy

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3