Polymer-capped gold nanoparticles as nanozymes with improved catalytic activity for the monitoring of serum ciprofloxacin

Author:

Cheng Cheng12,Qiao Juan13,Zhang Hongyi2ORCID,Zhao Zhenwen13ORCID,Qi Li13ORCID

Affiliation:

1. Key Lab of Analytical Chemistry for Living Bio-systems, Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, Beijing 100190, P.R. China

2. College of Chemistry & Environmental Science, Hebei University, Baoding 071002, P. R. China

3. School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, P.R. China

Abstract

PAM@AuNPs showed enzyme-simulation characteristic in TMB oxidation. Upon the improvement of its POD-like activity by drug CIP, a protocol for the selective and sensitive monitoring of CIP in rat-serum was constructed.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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