Synthesis, characterization and biological activity of bis[3-ethyl-4-aryl-5-(2-methoxypyridin-5-yl)-1-propyl-1,3-dihydro-2H-imidazol-2-ylidene]gold(i) complexes-Reference-Cited by-同舟云学术

Synthesis, characterization and biological activity of bis[3-ethyl-4-aryl-5-(2-methoxypyridin-5-yl)-1-propyl-1,3-dihydro-2H-imidazol-2-ylidene]gold(i) complexes

Published:2021 Issue:12 Volume:50 Page:4270-4279
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Gallati Caroline Marie¹²³⁴⁵,Goetzfried Sina Katharina¹²³⁴⁵^ORCID,Ortmeier Anna¹²³⁴⁵,Sagasser Jessica¹²³⁴⁵,Wurst Klaus⁶⁷⁴⁵⁸^ORCID,Hermann Martin⁹¹⁰⁵⁸,Baecker Daniel¹²³⁴⁵,Kircher Brigitte¹¹⁵⁸¹²¹³^ORCID,Gust Ronald¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry

2. Institute of Pharmacy

3. Center for Molecular Biosciences Innsbruck

4. University of Innsbruck

5. 6020 Innsbruck

6. Institute for General

7. Inorganic and Theoretical Chemistry

8. Austria

9. Department of Anesthesiology and Critical Care Medicine

10. Medical University Innsbruck

11. Tyrolean Cancer Research Institute

12. Immunobiology and Stem Cell Laboratory

13. Department of Internal Medicine V (Hematology and Oncology)

Abstract

A series of bis[3-ethyl-4-aryl-5-(2-methoxypyridin-5-yl)-1-propyl-1,3-dihydro-2H-imidazol-2-ylidene]gold(i) complexes was synthesized and evaluated for the anti-cancer properties in sensitive and resistant ovarian carcinoma and leukemia cell lines.

Funder

Österreichische Forschungsförderungsgesellschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D0DT03902K

Reference52 articles.

1. Platinum Compounds: a New Class of Potent Antitumour Agents

2. Current Status of Platinum-Based Antitumor Drugs

3. Update of the Preclinical Situation of Anticancer Platinum Complexes: Novel Design Strategies and Innovative Analytical Approaches

4. New Cisplatin Analogues—On the Way to Better Antitumor Agents

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