Pectin limits epithelial barrier disruption by Citrobacter rodentium through anti-microbial effects
Author:
Affiliation:
1. Immunoendocrinology
2. Division of Medical Biology
3. Department of Pathology and Medical Biology
4. University Medical Center Groningen
5. Groningen
6. Faculty of Applied Biological Sciences
7. Gifu University
8. Gifu City 501-1193
9. Japan
Abstract
Pectins inhibit the growth of C. rodentium in vitro, preventing attachment of C. rodentium to CMT93 epithelial cells. Through these antimicrobial effects, pectins protect the epithelium from C. rodentium-induced barrier dysfunction and damage.
Funder
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02605K
Reference36 articles.
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2. Citrobacter rodentium: infection, inflammation and the microbiota
3. A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
4. Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota
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