One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment
Author:
Affiliation:
1. State Key Laboratory of Pharmaceutical Biotechnology
2. Institute of Plant Molecular Biology
3. School of Life Sciences
4. Nanjing University
5. Nanjing 210023
Abstract
In a formic acid–H2O solution (60% : 40%), most aromatic aldehydes react efficiently with hydroxylamine hydrochloride and sodium acetate to form nitriles, where formic acid acts as both catalyst and solvent.
Funder
National Natural Science Foundation of China
Central University Basic Research Fund of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA03559B
Reference23 articles.
1. Difluorocarbene-Based Cyanation of Aryl Iodides
2. Vapour phase ammoxidation of toluene over vanadium oxide supported on Nb2O5–TiO2
3. Recent developments and perspectives in palladium-catalyzed cyanation of aryl halides: synthesis of benzonitriles
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